Calculating AUC (Linear and Log-linear)
AUC calculations are simple but nuanced. In this blog, we look at how to calculate…
Nathan Teuscher2025年4月2日
Accumulation: What It Means and How to Calculate It
2025年4月2日 In this blog, we look closely at drug accumulation ratio, to help…
Nathan Teuscher2025年4月2日
Demystifying CDISC, SDTM, and ADaM
Breaking down the basics of CDISC’s CDASH, SDTM and ADaM standards, to help you understand…
Nathan Teuscher2024年5月22日
9 Frequently Misunderstood Concepts in PK/PD Modeling
In teaching pharmacometrics, I've noticed that scientists have difficulty with certain PK/PD modeling concepts. Maybe…
Nathan Teuscher2015年11月3日
9 Things Your Boss Wishes You Knew About PK/PD Modeling
Over the course of my career, I have taught the theory and practical applications of PK/PD…
Nathan Teuscher2015年9月15日
Derivation for Logarithmic Trapezoidal AUC Calculation
Calculating area under the curve requires the use of two separate equations: one is follows…
Nathan Teuscher2015年8月5日
Calculating the Elimination Rate Constant
The elimination rate constant is the rate at which drug is cleared from the body…
Nathan Teuscher2015年2月2日
Adding a Placebo Component to Your PK/PD Model in Phoenix
PK/PD modeling is an exciting are of research in clinical pharmacology. Most often we try…
Nathan Teuscher2014年8月20日
Bioanalytical Calibration Curves
At the request of a reader, I have decided to extend my series on bioanalysis…
Nathan Teuscher2014年8月12日
Radiometric Analysis
One of the oldest methods used for the quantitation of drug molecules is radiometric analysis.…
Nathan Teuscher2014年7月29日
