ACoP14 2023
We are excited to be presenting at this conference
Workshop: Pre-Meeting Workshop (8 am – 5 pm ET) – Model-Based Meta-Analysis (MBMA): Concepts, Methodologies, and Hands-on Workshop.
Matt Zierhut, VP IDD and Jaap Mandema, CIO
Workshop: Pre-Meeting Workshop (8 am – 5 pm ET) – Simcyp Designer PBPK-QSP Focused Workshop
Tariq Abdulla, Associate Principal Scientist and Frederic Bois, Sr. Sci Advisor and Head of Mechanistic Modeling
Demo: QSP/Simcyp Designer: A graphical editor to seamlessly integrate QSP models with Simcyp Simulator
Booth #3 & 4
Concurrent Session 1B – Moving Boundaries: Towards Virtual Twin Patients in Clinical Trials and Precision Medicine for CNS Disorders.
Hugo Geerts, PhD
|Head of Neuroscience, QSP
Concurrent Session 1B – MIDD V2.0: Integrating Mechanistic Modeling and Artificial Intelligence.
Piet van der Graaf, PharmD, PhD
|Senior Vice President, Quantitative Systems Pharmacology
Demo: PMX Pharmacometrics Tools: Tailored for all user levels. Explore our new machine learning model selection feature in Pirana, along with advanced R, Shiny, and R Markdown reporting.
Booth #3 & 4
Demo: QSP Designer/Neuro: Platform offering a powerful tool to predict the effect of amyloid antibodies on biomarkers and side-effects in a clinical Alzheimer population in both trial design and real-world treatment.
Booth #3 & 4
Demo: CODEX Analytics App: Software to enable intuitive exploration and analyses of clinical outcomes databases
Booth #3 & 4
Demo: PMX Pharmacometrics Tools: Tailored for all user levels. Explore our new machine learning model selection feature in Pirana, along with advanced R, Shiny, and R Markdown reporting.
Booth #3 & 4
Demo: PMX Pharmacometrics Tools: Tailored for all user levels. Explore our new machine learning model selection feature in Pirana, along with advanced R, Shiny, and R Markdown reporting.
Booth #3 & 4
Demo: QSP Model of Complement System (CS): Complement pathway in immune defense.
Booth #3 & 4
IsoP Trainee Communication Challenge
Certara Representatives: Suzanne Minton, PhD and Mirjam Trame, Pharm D., PhD
Poster Presentation: Dose Guidance for a Novel Combination Therapy to Treat Head and Neck Squamous Cell Carcinoma (HNSCC) for Patients with HRAS/PIK3CA Variants Using a Quantitative Systems Pharmacology (QSP) Model
Jaehee Shim, Douglas Chung, Piet H van der Graaf
Poster Presentation: Exploring treatment guidelines for amyloid therapies in Alzheimer’s Disease Using Predictive Quantitative System Pharmacology Modeling
Hugo Geerts, Rachel Rose, Piet van der Graaf
Poster Presentation: A population-based approach predicts COVID-19 paediatric immunobridging trial outcomes using a QSP model of Tozinameran mRNA vaccine
Dennis Reddyhoff, Piet H. van der Graaf, Andrzej Kierzek
Population Pharmacokinetic Modeling of Dordaviprone in Healthy Adult Participants and Adult and Pediatric Patients with Solid Tumors.
Laura E. Strong, Shamia Faison, Tim Tippin, Tom Brundage, Odin Naderer, and Ayman Akil
Certara & Chimerix
Evaluation of the Boruta Machine Learning Algorithm for Covariate Selection
Ayman Akil, Vincent Duval, Nathan Teuscher, Floris Fauchet, Anna Largajolli, Ibtissem Rebai
Co-Sponsor International Masquerade Social Event
Demo: QSP/Simcyp Designer: A graphical editor to seamlessly integrate QSP models with Simcyp Simulator.
Booth #3 & 4
Demo: PMX Pharmacometrics Tools: Tailored for all user levels. Explore our new machine learning model selection feature in Pirana, along with advanced R, Shiny, and R Markdown reporting.
Booth #3 & 4
Demo: QSP/Simcyp Designer: A graphical editor to seamlessly integrate QSP models with Simcyp Simulator.
Booth #3 & 4
Demo: Vachette – Discover a new and innovative method for visualizing and communicating models with covariate effects made available within the ‘vachette’ R package.
Booth #3 & 4
Session: Application of PBPK model in predicting TP-DI with cytokine modulators
Xian Pan
|Associate Principal Scientist
Demo: PMX Pharmacometrics Tools: Tailored for all user levels. Explore our new machine learning model selection feature in Pirana, along with advanced R, Shiny, and R Markdown reporting.
Booth #3 & 4
Session: Predicting Disease Activity Scores in Inflammatory Bowel Disease by Connecting Simulated Tissue Biomarkers of a Virtual Population to Clinical Biomarkers and Outcomes Using a Novel Algorithm
Doug Chung
|Research Scientist, QSP
Session: Roller Coaster 1
Co Chair: Piet van der Graaf, PharmD, PhD
|Senior Vice President, Quantitative Systems Pharmacology
Demo: QSP model of Irritable Bowel Disease (IBD): Auto-immune disease of digestive track.
Booth #3 & 4
Poster Presentation: The interaction of core modules as a basis for elucidating network behavior determining Parkinson’s disease pathogenesis
Suruchi Bakshi
|Principal Scientist QSP
Poster Presentation: Predicting the impact of Haemodialysis with Simcyp Designer
Tariq Abdulla
|Associate Principal Scientist
Poster Presentation: A Quantitative Systems Pharmacology (QSP) Model to Investigate the Efficacy of a Novel Enzyme Replacement Therapy for Classical Homocystinuria (HCU)
Robert Mines, Douglas Chung, Maryam Khalifa, Piet H van der Graaf
Poster Presentation: NPSA: Nonparametric Simulated Annealing for Global Optimization
Ron Chung
|Research Scientist
Population Pharmacokinetics Analysis of Bardoxolone Methyl in Healthy Subjects and Subjects with Chronic Kidney Diseases.
Scott M. Hynes, Hamim Zahir, Aparna Shinde, Yu-Wei Lin, Laura Strong, Mayumi Hasegawa, William Copalu, and Nathan Teuscher. Reata Pharmaceuticals & Certara
Pharmacometric Model to Describe the Relationship between Bardoxolone Methyl Exposure and eGFR Changes in Patients with Chronic Kidney Disease at Risk of Rapid Progression.
Scott M. Hynes, Hamim Zahir, Aparna Shinde, Laura Strong, Nathan Teuscher, William Copalu, and Marc Pfister
Reata Pharmaceuticals & Certara