International PBPK Conference

As the Senior Vice President of Research & Development (SVP) and Chief Scientific Officer at Certara, he facilitates the incorporation and integration of the latest advances in translational modelling to bio-simulation platforms offered by Certara to its clients, with the aim of accelerating the development and regulatory approval of safer drug products and bringing them to the patients.

Amin was co-founder of two spin-off companies from the University of Sheffield (Simcyp Limited [now part of Certara Inc]) and Diurnal Limited [now part of Neurocrine Bioscience]). As a leader in the field of Physiologically-based Pharmacokinetics (PBPK) and Quantitative Systems Pharmacology (QSP), he is internationally recognized for his expertise in translational modelling to predict the behavior of drugs in human body, and understanding the associated inter-individual variabilities. He was one of the founding editors of Pharmacometrics and System Pharmacology and serves on the Editorial Boards of several other journals.

The Institute of Scientific Information (ISI, Clativate) listed Amin as one of the world’s most highly cited researchers (under ‘Pharmacology & Toxicology’) in 2017. Amin is also at 0.07% top rank of the Highly Cited Researchers List by Stanford University (published by Elsevier) for Pharmacology (2023). He has published over 330 peer reviewed highly influential scientific articles (>24,500 citations, h-index = 85, Google Scholar).

As the Director of Centre for Applied Pharmacokinetic Research (CAPKR) at the University of Manchester, Amin collaborates with many pharmaceutical companies with a view to transfer latest scientific applications into modern drug development. The work of Professor Rostami covers wide areas of drug development over the last 30 years, ranging from pharmaceutics (e.g. bioavailability and bioequivalence) to clinical pharmacology (e.g. mixture pharmacology of drug/metabolites), translational and systems pharmacology (e.g. quantitative proteomics of enzymes and transporter for in vitro to in vivo (IVIVE) scaling).

Dr. Jameiは、Simcypソフトウェアのデザイン、開発、実装に重点的に取り組んでいる約50名の科学者、35名のソフトウェア開発者およびテスターからなるチームを率いています。

Hannahは、グローバル製薬企業に20年以上の勤務し、特にPBPKおよびPKPDモデリングにおいて豊富な知識と実績を誇ります。PBPK/PKPDモデリングやその他DMPK関連分野に関する論文を70本以上発表しており、モデリング＆シミュレーションを通じて医薬品の研究開発プログラムに大きな影響を与えてきました。