Safety issues account for about a quarter of the attrition in drug projects, and can arise from either the primary or secondary pharmacology. ToxStudio™ is an integrated modelling & simulation platform for safety pharmacology and toxicology, facilitating quantitative translation from in vitro and in vivo data. Its first module, Secondary Intelligence™, manages and visualizes secondary pharmacology readouts, provides information on potential ADRs and assesses the likelihood of them occurring.