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ホーム / コンテンツ / オンデマンド・ウェビナー / Avoid the valley of death – increase confidence in translational research using biosimulation(死の谷を避ける - バイオシミュレーションを用いトランスレーショナルリサーチの信頼性を向上させる)

Avoid the valley of death – increase confidence in translational research using biosimulation(死の谷を避ける - バイオシミュレーションを用いトランスレーショナルリサーチの信頼性を向上させる)


オンデマンド・ウェビナー

The attrition rate of drug programs in early-stage development is high, with two-thirds of preclinical programs failing to move successfully to Phase 1. How do we better inform translational R&D decisions to de-risk investments and help increase probability of success?

Physiologically-based pharmacokinetic (PBPK) modeling and simulation is a regulatory-adopted, versatile tool in drug development that helps answer a myriad of “what if” questions without clinical testing. PBPK can also be used by discovery and translational scientists to increase confidence for pre-IND decisions, including:

  • First-in-human dose prediction
  • Early drug-drug interaction screening
  • Compound prioritization and selection
  • Early formulation work

Join this webinar to learn about using PBPK software, Simcyp Discovery Simulator for first-in-human dose prediction to help avoid the valley of death, crossing from preclinical to clinical research.

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