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A Bottom-up Whole-body Physiologically-based Pharmacokinetic Model to Mechanistically Predict Tissue Distribution and the Rate of Subcutaneous Absorption of Therapeutic Proteins

Author(s): Katherine Gill, Iain Gardner, Linzhong Li, Masoud Jamei

Year: 2016年1月1日

Redefining Regulatory Strategy with MIDD: Insights from the Draft ICH M15 Guidance

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A Bottom-up Whole-body Physiologically-based Pharmacokinetic Model to Mechanistically Predict Tissue Distribution and the Rate of Subcutaneous Absorption of Therapeutic Proteins

A Bottom-up Whole-body Physiologically-based Pharmacokinetic Model to Mechanistically Predict Tissue Distribution and the Rate of Subcutaneous Absorption of Therapeutic Proteins

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Redefining Regulatory Strategy with MIDD: Insights from the Draft ICH M15 Guidance

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