CoMSIA Study on Substituted Aryl Alkanoic Acid Analogs as GPR40 Agonists

GPR40, a G-protein-coupled receptor has been well established to play a crucial role in regulating blood glucose levels. Hence, GPR40 is a potential target for future antidiabetic agents. The present 3D QSAR study is aimed at delineating structural parameters governing GPR40 agonistic activity.



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