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Modeling & Simulation Relating Survival to Tumor Growth Inhibition in Patients

The published OS model and resultant simulations can be leveraged to support Phase II design and predict expected OS and HR (based on early observed TGI data obtained in Phase II or Phase III studies), thereby informing important mRCC development decisions, e.g., Go/No Go and dose regimen selection.

Author(s): Laurent Claret, Francois Mercier, Brett Houk, Peter Milligan, Rene Bruno

Year: 2015年9月1日

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