In Vitro to Human In Vivo Translation—Pharmacokinetics and Pharmacodynamics of Quinidine

The translational sciences aim to transfer results from basic research to the treatment of animals or patients. One of the approaches that could be utilized to achieve this goal is the in vitro in vivo extrapolation (IVIVE) of pharmacokinetic (PK) and pharmacodynamic (PD) properties using in silico methods. Such methodology, if properly applied, could help substantially … Continued

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