Pharmacokinetic Predictions in Children by Using the Physiologically-based Pharmacokinetic Modeling

Nowadays, 50-90% of drugs used in children have never been actually studied in this population. Consequently, either our children are often exposed to the risk of adverse drug events or to lack of efficacy, or they are unable to benefit from a number of therapeutic advances offered to adults, as no clinical study has been properly performed in children. Actually … Continued

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