Curcumin Induces Caspase-3-dependent Apoptotic Pathway but Inhibits DNA Fragmentation Factor 40/Caspase-activated DNase Endonuclease in Human Jurkat Cells

Curcumin is a natural pigment that has been shown to induce cell death in many cancer cells; however, the death mode depends on the cell type and curcumin concentration. Here we show that, in Jurkat cells, 50 µmol/L curcumin severely lowers cell survival and induces initial stage of chromatin condensation. It also induces caspase-3, which … Continued

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