Poster

A Quantitative Systems Pharmacology Comparison Of Tau-targeted Therapeutic Strategies In Alzheimer’s Disease

Certara's quantitative systems pharmacology (QSP) model compares tau-targeted therapeutic strategies in Alzheimer's Disease, including antibodies,…

Certara2026年7月16日

Blog

QSP modeling for Parkinson’s disease: Solving the synthetic control challenge in clinical trials

QSP modeling for Parkinson’s disease tackles optimized standard-of-care, placebo response, and missing biomarkers. See how…

Certara2026年6月11日

Publication

Oxford Academic, Neuro-Oncology Pediatrics – BRAF pub: Growth recovery in patients with BRAF-altered pediatric low-grade glioma following treatment with tovorafenib

This publication reports a pooled retrospective analysis evaluating growth patterns in children with B-Raf proto-oncogene…

Dorottya Gui-Bodnar2026年5月28日

Blog

How quantitative systems pharmacology addresses key challenges in Alzheimer’s drug development

Quantitative Systems Pharmacology (QSP) helps address key challenges in Alzheimer’s disease drug development, including tau…

Certara2026年2月2日

Publication

Modeling amyloid plaque turnover dynamics improves characterization of drug effects

Researchers modeled how amyloid plaques form and clear in Alzheimer’s disease, helping explain how treatments…

Certara2025年11月26日

Case Study

重要な医薬品：Biohaven社の Nurtec™ 医薬品開発のジャーニー

In February 2020, Biohaven Pharmaceuticals announced that the U.S. Food and Drug Administration (FDA) approved…

Certara2024年8月15日

Case Study

Simcyp Simulator を使用した小児における Guanfacine の DDI 責任の判定

Guanfacine (Intuniv® XR) extended release (GXR) is an orally administered, selective alpha2A-adrenergic receptor agonist, non-stimulant…

Certara2021年8月26日

Case Study

Using a PBPK-PD Receptor Occupancy Model to Determine the Optimal Dose of Radiprodil for Neonates

Radiprodil is a selective allosteric modulator of the NR2B N-methyl-D-aspartate receptor GluN2B-NMDA that was being…

Certara2021年8月26日

Case Study

Bridging Formulations of Quetiapine for Children with Schizophrenia or Bipolar Disorder

Quetiapine is an atypical antipsychotic for treating schizophrenia, bipolar depression, bipolar mania that helps to…

Certara2021年8月26日

Case Study

Simcypの年齢定義機能により、新生児へのエベロリムス投与が容易に

Everolimus (Afinitor®) was recently approved as adjunctive therapy for tuberous sclerosis complex (TSC)-associated partial seizures…

Certara2021年8月26日

中枢神経系(CNS)

A Quantitative Systems Pharmacology Comparison Of Tau-targeted Therapeutic Strategies In Alzheimer’s Disease

QSP modeling for Parkinson’s disease: Solving the synthetic control challenge in clinical trials

Oxford Academic, Neuro-Oncology Pediatrics – BRAF pub: Growth recovery in patients with BRAF-altered pediatric low-grade glioma following treatment with tovorafenib

How quantitative systems pharmacology addresses key challenges in Alzheimer’s drug development

Modeling amyloid plaque turnover dynamics improves characterization of drug effects

重要な医薬品：Biohaven社の Nurtec™ 医薬品開発のジャーニー

Simcyp Simulator を使用した小児における Guanfacine の DDI 責任の判定

Using a PBPK-PD Receptor Occupancy Model to Determine the Optimal Dose of Radiprodil for Neonates

Bridging Formulations of Quetiapine for Children with Schizophrenia or Bipolar Disorder

Simcypの年齢定義機能により、新生児へのエベロリムス投与が容易に

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