VIVD: a Virtual In Vitro Distribution Model for Predicting Intra- and Sub-Cellular Concentrations in Toxicity Assays Poster VIVD: a Virtual In Vitro Distribution Model for Predicting Intra- and Sub-Cellular Concentrations in Toxicity Assays Danielle Pillsbury2019年8月29日
On Early Paediatric Study Design: Sample Size Calculation using a PBPK Approach within the Simcyp Simulator Poster On Early Paediatric Study Design: Sample Size Calculation using a PBPK Approach within the Simcyp Simulator Danielle Pillsbury2019年8月29日
Development and Integration of a Dynamic Lactation Functionality within a Full PBPK Model Poster Development and Integration of a Dynamic Lactation Functionality within a Full PBPK Model Danielle Pillsbury2019年8月29日
Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach for the Prediction of Small Intestinal Precipitation of Poorly Soluble Drugs – A Simulation Study of Posaconazole Using the Simcyp ADAM Model Poster Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach for the Prediction of Small Intestinal Precipitation of Poorly Soluble Drugs – A Simulation Study of Posaconazole Using the Simcyp ADAM Model Danielle Pillsbury2019年8月28日
Simulating the effect of anti-diabetic drugs on ATP-sensitive potassium (KATP) channels inhibition in a human cardiac cell model (ORd) Poster Simulating the effect of anti-diabetic drugs on ATP-sensitive potassium (KATP) channels inhibition in a human cardiac cell model (ORd) Danielle Pillsbury2019年8月28日
Prediction of Erythropoietin Disposition in a Paediatric Population Using SimCYP® Poster Prediction of Erythropoietin Disposition in a Paediatric Population Using SimCYP® Danielle Pillsbury2019年8月28日
An in silico PBPK-PD coupled approach to assess Zolpidem effect on pre-clinically and clinically measured cardiac repolarisation parameters in the absence and presence of a circadian model of plasma ion concentration. ポスター An in silico PBPK-PD coupled approach to assess Zolpidem effect on pre-clinically and clinically measured cardiac repolarisation parameters in the absence and presence of a circadian model of plasma ion concentration. Danielle Pillsbury2019年8月28日
Repolarisation Rate: an integrative biomarker of cardiac action potential repolarisation Poster Repolarisation Rate: an integrative biomarker of cardiac action potential repolarisation Danielle Pillsbury2019年8月28日
Towards unravelling the mechanism of Cardiotoxicity of Citalopram: Utilisation of mechanistic cardiac electrophysiology modelling with Simcyp Cardiac Safety Simulator to explore various hypotheses Poster Towards unravelling the mechanism of Cardiotoxicity of Citalopram: Utilisation of mechanistic cardiac electrophysiology modelling with Simcyp Cardiac Safety Simulator to explore various hypotheses Danielle Pillsbury2019年8月28日
Mechanistic modelling of dermal drug absorption using the Simcyp Multi-phase Multi-layer MechDermA model: Case study of a transdermal patch formulation of weak base drug timolol Poster Mechanistic modelling of dermal drug absorption using the Simcyp Multi-phase Multi-layer MechDermA model: Case study of a transdermal patch formulation of weak base drug timolol Danielle Pillsbury2019年8月28日
