What Can We Learn from Dose Normalization?
Dose normalization is a common calculation performed with pharmacokinetic parameters. The general process is to…
Certara2014年5月19日
Extrapolating AUC to Infinity
Area under the curve or AUC is a pharmacokinetic statistic used to describe the total…
Certara2014年2月24日
Hyperlinking: Making the Most of Navigation in eCTD Submissions
When authors generate documents intended for electronic submission they use blue-colored font to indicate where…
Certara2014年2月5日
What is GLP (Good Laboratory Practice)?
Good laboratory practice or GLP is a set of principles intended to assure the quality…
Certara2013年12月9日
Understanding Steady State Pharmacokinetics
“Steady state” is an important term in pharmacokinetics, but it can often seem a bit…
Certara2013年11月25日
Mean Residence Time (MRT): Understanding How Long Drug Molecules Stay in the Body
When I first began learning about pharmacokinetics, I was often confused by the mean residence…
Certara2013年3月28日
What is a Loading Dose?
Drug therapy in chronic disease situations requires systemic drug levels to reach target steady-state levels…
Certara2013年3月22日
Nonlinear PK: What Does That Mean?
You may come across a phrase like the following and wonder what it means: “……
Certara2013年2月17日
Calculating Urine PK Parameters
Pharmacokinetic analysis normally focuses on systemic exposure to a drug; however, much can be learned…
Certara2012年12月6日
Bioavailability
Discover bioavailability in pharmacokinetics, its types, the first-pass effect, and calculations. Explore tools for accurate…
Certara2012年11月4日
