Category: 資料

The Clinical Drug Interaction Dataset contains study results from drug-drug, drug-food, drugnatural products, drug-excipient interaction studies, and case reports.

The Drug Metabolism Dataset contains results from in vitro metabolism studies, where a drug is tested as an inhibitor/activator/inducer (precipitant) or a substrate (object) for a given human drug metabolizing enzyme (including variants).

The Clinical Pharmacogenetic (PGx) Dataset provides in-depth analysis of the impact of geneticvariants of enzymes and transporters on the PK, PD, and safety of drugs in various populations.Available information comes from publications and NDA reviews describing gene-drug interactions(GDI), ethnicity-drug interactions, and case reports.

The Drug Transporter Dataset contains results from in vitro transporter studies, where a drug istested as an inhibitor (precipitant) or a substrate (object) for a given human drug transporter(including variants).

The Clinical Organ Impairment Dataset contains study results from renal and hepatic impairmentstudies.