Applications of Quantitative Systems Pharmacology Modeling for Vaccine Development Poster Applications of Quantitative Systems Pharmacology Modeling for Vaccine Development Vaccines play a crucial role in preventing diseases and thereby saving countless lives. To prevent…Danielle Pillsbury2025年4月24日
Mechanistic Modeling Guides Bispecific Antibody Design and Target Selection for Maximizing Therapeutic Window Poster 機械的モデリングが二重特異性抗体デザインと標的選択を導き、治療濃度域を最大化 Therapeutic antibodies have shown promise in treating diseases such as cancer, but selectivity remains a…Danielle Pillsbury2025年3月28日
Comparison Across Anti-PD-1 Antibodies – Insights From QSP-Based Meta-Analysis Poster Comparison Across Anti-PD-1 Antibodies – Insights From QSP-Based Meta-Analysis Regulatory-ready systems modeling software to optimize drug developmentDiscover how Certara’s QSP Software can accelerate your…Danielle Pillsbury2025年3月2日
Simulations to Inform Dose Selection for a Phase 2b Trial Investigating TOUR006, a Fully Human Anti-IL6 Antibody, for Treatment of Thyroid Eye Disease Poster バセドウ病眼症の治療を目的とした完全ヒト型抗IL-6抗体TOUR006のフェーズ2b試験における用量選択を支援するためのシミュレーション Danielle Pillsbury2025年2月7日
Dose Guidance for a Novel Combination Therapy to Treat Head and Neck Squamous Cell Carcinoma (HNSCC) for Patients with HRAS/PIK3CA Variants Using a Quantitative Systems Pharmacology (QSP) Model Poster Dose Guidance for a Novel Combination Therapy to Treat Head and Neck Squamous Cell Carcinoma (HNSCC) for Patients with HRAS/PIK3CA Variants Using a Quantitative Systems Pharmacology (QSP) Model Danielle Pillsbury2025年1月16日
A Scalable Cloud Platform Accelerates QSP Virtual Patient Generation Poster A Scalable Cloud Platform Accelerates QSP Virtual Patient Generation Danielle Pillsbury2024年12月13日
Difference in efficacy between anti-PD-1 and anti-PD-L1 antibodies may be attributable to PD-1:PD-L2 complex inhibition, rather than differences in PD-1:PD-L1 inhibition Poster Difference in efficacy between anti-PD-1 and anti-PD-L1 antibodies may be attributable to PD-1:PD-L2 complex inhibition, rather than differences in PD-1:PD-L1 inhibition Danielle Pillsbury2024年12月13日
Cumulative drug binding to Cerebral Amyloid Angiopathy (CAA) predicts ARIA-E incidence for anti-Aβ antibodies in Alzheimer’s Disease Poster Cumulative drug binding to Cerebral Amyloid Angiopathy (CAA) predicts ARIA-E incidence for anti-Aβ antibodies in Alzheimer’s Disease Danielle Pillsbury2024年12月13日
QSP model of neuroinflammation: Effect of TREM2 stimulation on microglial activation and function in the context of Alzheimer’s disease Poster QSP model of neuroinflammation: Effect of TREM2 stimulation on microglial activation and function in the context of Alzheimer’s disease Danielle Pillsbury2024年12月13日
Population Pharmacokinetics (PopPK) of Revumenib in Patients with Relapsed/Refractory Acute Leukemias Poster Population Pharmacokinetics (PopPK) of Revumenib in Patients with Relapsed/Refractory Acute Leukemias Danielle Pillsbury2024年12月12日