Quantitative Systems Pharmacology (QSP) Summit 2025

Summary

The Quantitative Systems Pharmacology (QSP) Summit is a free conference dedicated to fostering an active community of industry and academic participants interested in topics relevant to QSP. In its eighth year, the QSP Summit is a one-day event featuring talks from key industry and academic researchers and networking time with peers.

開催日: 2025年4月10日 (木曜日)

開催時間 9am – 5pm ET

エリア： Le Meridien Boston Cambridge, 20 Sidney Street, Cambridge, MA 02139

講演者

Kerry Culm, Chief Development Officer at ModeX Therapeutics
Josh Apgar, VP of QSP Software and Products at Certara
Allison Claas, Sr Principal Scientist at Novartis
Anna Sher, Sr Director, QSP at GSK
Hojjat Bazzazi, Director, Quantitative Systems Pharmacology, at Moderna
Irina Kareva, Associate Director, Quantitative Pharmacology, at EMD Serono
Piet van der Graaf, Senior Vice President and Head of Quantitative Systems Pharmacology, Certara

Panelists:

Agenda

9:00 AM – 9:30 AM

Breakfast and Registration

9:30 AM – 9:45 AM

Opening remarks

Joshua Apgar, VP, Head of QSP Software, Certara

9:45 AM – 10:20 AM

QSP at Scale: Unlocking New Frontiers in Predictive Modeling

Piet van der Graaf, PharmD, PhD, FBPhS, Senior Vice President and Head of Quantitative Systems Pharmacology, Certara

10:20 AM – 10:55 AM

Application of Physiologically Based PK (PBPK) modeling in LNP based mRNA therapeutics

Hojjat Bazzazi, Director, Quantitative System Pharmacology, Moderna Therapeutics

10:55 AM – 11:25 AM

Break

11:25 AM – 12:00 PM

Modeling targeted protein degradation from cells to the clinic

Allison Claas, Sr Principal Scientist, Novartis

12:00 PM – 12:35 PM

Beyond Bispecifics: Using Quantitative Systems Pharmacology to Strategically Develop Tetraspecific T Lymphocyte Activation and Survival Enhancement Receptor (LASER) Abs for Solid Tumors

Kerry Culm, Chief Development Officer, ModeX Therapeutics

12:35 PM – 1:35 PM

Lunch

1:35 PM – 2:10 PM

QSP has come of age, now how do we scale?: A sneak peak at Certara IQ

Joshua Apgar, VP, Head of QSP Software, Certara

2:10 PM – 2:45 PM

Past, Present and Future Through the Lens of QSP and QST

Anna Sher, Sr Director, QSP, GSK

2:45 PM – 3:15 PM

Break

3:15 PM – 3:50 PM

Using Virtual Patients to Evaluate Dosing Strategies for Bispecifics with a Bell-Shaped Efficacy Curve

Irina Kareva, Associate Director, Quantitative Pharmacology, EMD Serono

3:50 PM – 4:50 PM

Panel Discussion

Panelists:

John M. Burke, Chief Pharmacology Officer – Fractional, Reverb Therapeutics
Karthik Venkatakrishnan, Vice President and Global Head of Quantitative Pharmacology, EMD Serono
Haojing Rong, Chief Development Officer, Stealth NewCo, Atlas Ventures