Population Pharmacokinetics of Vernakalant Hydrochloride Injection (RSD1235) in Patients with Atrial Fibrillation or Atrial Flutter Publication Population Pharmacokinetics of Vernakalant Hydrochloride Injection (RSD1235) in Patients with Atrial Fibrillation or Atrial Flutter Vernakalant hydrochloride is a novel, predominantly atrial-selective antiarrhythmic drug that effectively and rapidly terminates atrial…webdev2012年7月1日
Modeling and Simulation of Edoxaban Exposure and Response Relationships in Patients with Atrial Fibrillation Publication Modeling and Simulation of Edoxaban Exposure and Response Relationships in Patients with Atrial Fibrillation Edoxaban is a novel, orally available, highly specific direct inhibitor of factor Xa and is…webdev2012年5月1日
Therapeutic Index of Anticoagulants for Prevention of Venous Thromboembolism Following Orthopedic Surgery: A Dose-response Meta-analysis Publication Therapeutic Index of Anticoagulants for Prevention of Venous Thromboembolism Following Orthopedic Surgery: A Dose-response Meta-analysis Information on the comparative effectiveness of drugs is crucial for drug development decisions, in addition…webdev2011年12月1日
Model-based Development of Anacetrapib, a Novel Cholesteryl Ester Transfer Protein Inhibitor Publication Model-based Development of Anacetrapib, a Novel Cholesteryl Ester Transfer Protein Inhibitor A model-based strategy was used to inform the early clinical development of anacetrapib, a novel…webdev2011年6月1日
Systematic Review: Diagnostic Accuracy of Clinical Decision Rules for Venous Thromboembolism in Elderly Publication Systematic Review: Diagnostic Accuracy of Clinical Decision Rules for Venous Thromboembolism in Elderly Physicians committed to the care of elderly patients are challenged with the diagnosis of venous…webdev2011年4月1日
Meta-analysis of Thoracic Epidural Anesthesia Versus General Anesthesia for Cardiac Surgery Publication Meta-analysis of Thoracic Epidural Anesthesia Versus General Anesthesia for Cardiac Surgery A combination of general anesthesia (GA) with thoracic epidural anesthesia (TEA) may have a beneficial…webdev2011年2月1日
Modeling Disease Progression in Acute Stroke Using Clinical Assessment Scales Publication Modeling Disease Progression in Acute Stroke Using Clinical Assessment Scales This article demonstrates techniques for describing and predicting disease progression in acute stroke by modeling…webdev2010年12月1日
Randomised, Parallel-group, Multicenter, Multinational Phase 2 Study Comparing Edoxaban, an Oral Factor Xa Inhibitor, with Warfarin for Stroke Prevention in Patients with Atrial Fibrillation Publication Randomised, Parallel-group, Multicenter, Multinational Phase 2 Study Comparing Edoxaban, an Oral Factor Xa Inhibitor, with Warfarin for Stroke Prevention in Patients with Atrial Fibrillation The primary objective of this study was to compare the safety of four fixed-dose regimens…webdev2010年9月10日
Under-reporting of Venous and Arterial Thrombotic Events in Randomized Clinical Trials: A Meta-analysis Publication Under-reporting of Venous and Arterial Thrombotic Events in Randomized Clinical Trials: A Meta-analysis For the detection of unwanted outcomes of new interventions, physicians rely on adverse event reporting.…webdev2010年3月1日
Excluding Venous Thromboembolism Using Point of Care D-dimer Tests in Outpatients: A Diagnostic Meta-analysis Publication Excluding Venous Thromboembolism Using Point of Care D-dimer Tests in Outpatients: A Diagnostic Meta-analysis This article is a review the evidence on the diagnostic accuracy of the currently available…webdev2009年8月14日