Study Reanalysis Using a Mechanism-based Pharmacokinetic/Pharmacodynamic Model of Pramlintide in Subjects with Type 1 Diabetes
This report describes a pharmacokinetic/pharmacodynamic model for pramlintide, an amylinomimetic, in type 1 diabetes mellitus…
Danielle Pillsbury2015年1月1日
Population Pharmacokinetic Analysis of Dutogliptin, a Selective Dipeptidyl Peptidase-4 Inhibitor
Dutogliptin is a selective dipeptidyl peptidase-4 inhibitor shown to be efficacious and safe in patients…
Danielle Pillsbury2014年7月14日
Pharmacometric Approaches to Guide Dose Selection of the Novel GPR40 Agonist TAK-875 in Subjects with Type 2 Diabetes Mellitus
The G-protein-coupled receptor 40 agonist (GPR40) TAK-875 is being developed as an adjunct to diet…
Danielle Pillsbury2013年1月9日
Population Pharmacokinetic Model for a Novel Oral Hypoglycemic Formed In Vivo: Comparing the Use of Active Metabolite Data Alone Versus Using Data of Upstream and Downstream Metabolites
The purpose of this analysis was to develop a population pharmacokinetic model for CS-917, an…
Danielle Pillsbury2012年3月1日
The Use of Biosimulation in the Design of a Novel Multilevel Weight Loss Maintenance Program for Overweight Children
Weight loss outcomes achieved through conventional behavior change interventions are prone to deterioration over time.…
Danielle Pillsbury2010年2月18日
CYP2D6 is Primarily Responsible for the Metabolism of Clomiphene
Clomiphene is a first line treatment for anovulation, a common cause of infertility. Response to…
Danielle Pillsbury2008年4月30日
