Model-Informed Drug Development Framework for the Development and Dose Optimization of Targeted Radiation Therapies Poster モデルを活かした医薬品開発(MIDD)の枠組みによる、標的放射線療法の開発と投与量の最適化 Danielle Pillsbury2024年11月22日
Augmented Definitive Screening Design Provides Efficient Phase 1 Selection of CAR T-cell and Lymphodepletion Regimen Poster Augmented Definitive Screening Design Provides Efficient Phase 1 Selection of CAR T-cell and Lymphodepletion Regimen Danielle Pillsbury2024年11月22日
Oncology MIDD Simulator, A User-Friendly Application for Overall Survival Forecasting in Early Oncology Trials Poster Oncology MIDD Simulator, A User-Friendly Application for Overall Survival Forecasting in Early Oncology Trials Danielle Pillsbury2024年11月22日
Quantitative Systems Pharmacology model for combined targeting of BAFF and CD40 pathways in systemic lupus erythematosus Poster Quantitative Systems Pharmacology model for combined targeting of BAFF and CD40 pathways in systemic lupus erythematosus Danielle Pillsbury2024年11月22日
Population pharmacokinetic modeling of niraparib to assess different absorption models Poster Population pharmacokinetic modeling of niraparib to assess different absorption models Danielle Pillsbury2024年11月22日
Recent applications of pharmacometrics and systems pharmacology approaches to improve and optimize drug therapy for pregnant and lactating women Publication 妊婦および授乳中の女性のための治療薬を改善および最適化するファーマコメトリクスとシステム薬理学アプローチの直近のアプリケーション The article "Recent Applications of Pharmacometrics and Systems Pharmacology Approaches to Improve and Optimize Drug…Danielle Pillsbury2024年11月18日
PBPK Modeling to Support Bioequivalence & Generic Product Approvals Blog PBPKモデル化による生物学的同等性評価およびジェネリック医薬品承認の支援 Physiologically-based pharmacokinetic modeling can be used to support bioequivalence (BE) assessment of complex and locally…Certara2024年11月12日
A Sequential Population Pharmacokinetic Model of Zilovertamab Vedotin in Patients with Hematologic Malignancies Extrapolated to the Pediatric Population Publication A Sequential Population Pharmacokinetic Model of Zilovertamab Vedotin in Patients with Hematologic Malignancies Extrapolated to the Pediatric Population Danielle Pillsbury2024年11月7日
Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody Publication Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody The article titled "Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a…Danielle Pillsbury2024年11月4日
Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women Publication Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women The article titled "Using PBPK modeling to supplement clinical data and support the safe and…Danielle Pillsbury2024年10月30日