The Effect of Plasmapheresis on Blood Pressure in Voluntary Plasma Donors Publication The Effect of Plasmapheresis on Blood Pressure in Voluntary Plasma Donors Donor plasmapheresis involves the removal of a weight-adjusted volume of plasma and the return of…Certara2015年1月1日
Population Dose-response Analysis of Daily Seizure Count Following Vigabatrin Therapy in Adult and Pediatric Patients with Refractory Complex Partial Seizures Publication Population Dose-response Analysis of Daily Seizure Count Following Vigabatrin Therapy in Adult and Pediatric Patients with Refractory Complex Partial Seizures Vigabatrin is an irreversible inhibitor of γ-aminobutyric acid transaminase (GABA-T) and is used as an…Certara2015年1月1日
Pharmacokinetics of Injectable, Long-acting Nevirapine for HIV Prophylaxis in Breastfeeding Infants Publication Pharmacokinetics of Injectable, Long-acting Nevirapine for HIV Prophylaxis in Breastfeeding Infants Mother-to-child transmission (MTCT) of HIV-1 remains a global health problem. The World Health Organization (WHO…Certara2015年1月1日
Onartuzumab with or without Bevacizumab in Combination with Weekly Paclitaxel Does Not Prolong QTc or Adversely Affect Other ECG Parameters in Patients with Locally Recurrent or Metastatic Triple-negative Breast Cancer Publication Onartuzumab with or without Bevacizumab in Combination with Weekly Paclitaxel Does Not Prolong QTc or Adversely Affect Other ECG Parameters in Patients with Locally Recurrent or Metastatic Triple-negative Breast Cancer The purpose of this study was to examine the potential effect of onartuzumab, when administered…Certara2014年12月17日
Pharmacokinetics of Vancomycin in Critically Ill Patients in Thailand Publication Pharmacokinetics of Vancomycin in Critically Ill Patients in Thailand The pharmacokinetics and pharmacodynamics of drugs in critically ill patients are difficult to predict due…Certara2014年12月1日
Characterization of the Transmembrane Transport and Absolute Bioavailability of the HCV Protease Inhibitor Danoprevir Publication Characterization of the Transmembrane Transport and Absolute Bioavailability of the HCV Protease Inhibitor Danoprevir Certara2014年12月1日
Pharmacokinetics and Pharmacodynamics of Setrobuvir, an Orally Administered Hepatitis C Virus Non-nucleoside Analog Inhibitor Publication Pharmacokinetics and Pharmacodynamics of Setrobuvir, an Orally Administered Hepatitis C Virus Non-nucleoside Analog Inhibitor Certara2014年12月1日
Meropenem in Children Receiving Continuous Renal Replacement Therapy: Clinical Trial Simulations Using Realistic Covariates Publication Meropenem in Children Receiving Continuous Renal Replacement Therapy: Clinical Trial Simulations Using Realistic Covariates Meropenem is frequently prescribed in children receiving continuous renal replacement therapy (CRRT). Fluid overload is…Certara2014年12月1日
Vigabatrin Pediatric Dosing Information for Refractory Complex Partial Seizures: Results from a Population Dose-response Analysis Publication Vigabatrin Pediatric Dosing Information for Refractory Complex Partial Seizures: Results from a Population Dose-response Analysis We predicted vigabatrin dosages for adjunctive therapy for pediatric patients with refractory complex partial seizures…Certara2014年12月1日
Modeling and Simulation for Medical Product Development and Evaluation: Highlights from the FDA-C-Path-ISOP 2013 Workshop Publication Modeling and Simulation for Medical Product Development and Evaluation: Highlights from the FDA-C-Path-ISOP 2013 Workshop Medical-product development has become increasingly challenging and resource-intensive. In 2004, the Food and Drug Administration…Certara2014年12月1日