Therapeutic Index of Anticoagulants for Prevention of Venous Thromboembolism Following Orthopedic Surgery: A Dose-response Meta-analysis Publication Therapeutic Index of Anticoagulants for Prevention of Venous Thromboembolism Following Orthopedic Surgery: A Dose-response Meta-analysis Information on the comparative effectiveness of drugs is crucial for drug development decisions, in addition…Certara2011年12月1日
A Dose-response Meta-analysis for Quantifying Relative Efficacy of Biologics in Rheumatoid Arthritis Publication A Dose-response Meta-analysis for Quantifying Relative Efficacy of Biologics in Rheumatoid Arthritis We present a dose-response meta-analysis to quantify relative efficacy of biologic disease-modifying antirheumatic drugs (DMARDs)…Certara2011年12月1日
Reducing Systems Biology to Practice in Pharmaceutical Company Research: Selected Case Studies Publication Reducing Systems Biology to Practice in Pharmaceutical Company Research: Selected Case Studies Reviews of the productivity of the pharmaceutical industry have concluded that the current business model…Certara2011年11月18日
What is Hysteresis in PK/PD Analysis? 技術情報 What is Hysteresis in PK/PD Analysis? I apologize to all my readers for such a long lapse between posts. After a…Certara2011年10月26日
Safety and Population Pharmacokinetic Analysis of Intravenous Acetaminophen in Neonates, Infants, Children, and Adolescents with Pain or Fever Publication Safety and Population Pharmacokinetic Analysis of Intravenous Acetaminophen in Neonates, Infants, Children, and Adolescents with Pain or Fever The administration of acetaminophen via the oral and rectal routes may be contraindicated in specific…Certara2011年10月16日
Pharmacokinetics of SN2310, an Injectable Emulsion that Incorporates a New Derivative of SN-38 in Patients with Advanced Solid Tumors Publication Pharmacokinetics of SN2310, an Injectable Emulsion that Incorporates a New Derivative of SN-38 in Patients with Advanced Solid Tumors SN2310 is an injectable emulsion composed of vitamin E, a succinate derivative, as well as…Certara2011年10月1日
Ammonia Control in Children with Urea Cycle Disorders (UCDs); Phase 2 Comparison of Sodium Phenylbutyrate and Glycerol Phenylbutyrate Publication Ammonia Control in Children with Urea Cycle Disorders (UCDs); Phase 2 Comparison of Sodium Phenylbutyrate and Glycerol Phenylbutyrate Twenty four hour ammonia profiles and correlates of drug effect were examined in a phase…Certara2011年8月1日
How Can PK/PD Analysis Add Value to Patient Care? 技術情報 How Can PK/PD Analysis Add Value to Patient Care? In May 2011, T.J. Smith and B.E. Hillner published an opinion piece in the New…Certara2011年7月11日
What is Curve Stripping? 技術情報 What is Curve Stripping? The process of curve stripping is used in both compartmental and non-compartmental analysis. Each pharmacokinetic…Certara2011年7月6日
Pharmacokinetic-pharmacodynamic Disease Progression Model for Effect of Etanercept in Lewis Rats with Collagen-induced Arthritis Publication Pharmacokinetic-pharmacodynamic Disease Progression Model for Effect of Etanercept in Lewis Rats with Collagen-induced Arthritis The purpose of this study was to develop a pharmacokinetic-pharmacodynamic disease progression (PK/PD/DIS) model to…Certara2011年7月1日