Clinical Tolerance and Toxicity of Intravenous Baclofen: A Pilot Study in a Canine Model Publication Clinical Tolerance and Toxicity of Intravenous Baclofen: A Pilot Study in a Canine Model Assess safety and tolerance of intravenous (IV) baclofen using a dog model. Prospective pharmacokinetic study…Certara2011年7月1日
Model-based Development of Anacetrapib, a Novel Cholesteryl Ester Transfer Protein Inhibitor Publication Model-based Development of Anacetrapib, a Novel Cholesteryl Ester Transfer Protein Inhibitor A model-based strategy was used to inform the early clinical development of anacetrapib, a novel…Certara2011年6月1日
Pharmacokinetics and Pharmacodynamics of TBR-652, a Novel CCR5 Antagonist, in HIV-1-Infected, Antiretroviral Treatment-experienced and CCR5 Antagonist-naive Patients Publication Pharmacokinetics and Pharmacodynamics of TBR-652, a Novel CCR5 Antagonist, in HIV-1-Infected, Antiretroviral Treatment-experienced and CCR5 Antagonist-naive Patients TBR-652 is a novel CCR5 antagonist with potent in vitro anti-HIV activity. The objective of…Certara2011年4月12日
What to Do with Those BLQs! BlogKnowledge Base What to Do with Those BLQs! BLQ values are like those pimples we used to get as teenagers. They…Certara2011年4月6日
The Difference Between Vd and Vss BlogKnowledge Base The Difference Between Vd and Vss There are many terms used to represent volume of distribution, but two common ones are…Certara2011年3月31日
What is Shrinkage? 技術情報 What is Shrinkage? In 2007, Mats Karlsson and Radojka Savic published a perspective in Clinical Pharmacology & Therapeutics…Certara2011年3月29日
Is a Monte Carlo Simulation an Exotic Drink? 技術情報 Is a Monte Carlo Simulation an Exotic Drink? The term “Monte Carlo simulation” is often used in the modeling and simulation literature with…Certara2011年3月21日
What is WinNonlin? 技術情報 What is WinNonlin? A reader suggested that I write a similar post about WinNonlin. Great idea! Thank you!…Certara2011年3月16日
What is the Difference Between Individual and Population PK? 技術情報 What is the Difference Between Individual and Population PK? Pharmacokinetic analysis is often broken into two areas … “PK” and “population PK”. Sometimes the…Certara2011年3月14日
Blood or Plasma? Which Should You Assay for Drug Concentration? 技術情報 Blood or Plasma? Which Should You Assay for Drug Concentration? Explore blood vs. plasma drug concentration assays. Learn their differences, relationships, and impact on accurate…Certara2011年2月19日