Development and Integration of a Dynamic Lactation Functionality within a Full PBPK Model Poster Development and Integration of a Dynamic Lactation Functionality within a Full PBPK Model Certara2019年8月29日
Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach for the Prediction of Small Intestinal Precipitation of Poorly Soluble Drugs – A Simulation Study of Posaconazole Using the Simcyp ADAM Model Poster Physiologically-Based Pharmacokinetic (PBPK) Modelling Approach for the Prediction of Small Intestinal Precipitation of Poorly Soluble Drugs – A Simulation Study of Posaconazole Using the Simcyp ADAM Model Certara2019年8月28日
Simulating the effect of anti-diabetic drugs on ATP-sensitive potassium (KATP) channels inhibition in a human cardiac cell model (ORd) Poster Simulating the effect of anti-diabetic drugs on ATP-sensitive potassium (KATP) channels inhibition in a human cardiac cell model (ORd) Certara2019年8月28日
Prediction of Erythropoietin Disposition in a Paediatric Population Using SimCYP® Poster Prediction of Erythropoietin Disposition in a Paediatric Population Using SimCYP® Certara2019年8月28日
An in silico PBPK-PD coupled approach to assess Zolpidem effect on pre-clinically and clinically measured cardiac repolarisation parameters in the absence and presence of a circadian model of plasma ion concentration. ポスター An in silico PBPK-PD coupled approach to assess Zolpidem effect on pre-clinically and clinically measured cardiac repolarisation parameters in the absence and presence of a circadian model of plasma ion concentration. Certara2019年8月28日
Repolarisation Rate: an integrative biomarker of cardiac action potential repolarisation Poster Repolarisation Rate: an integrative biomarker of cardiac action potential repolarisation Certara2019年8月28日
Towards unravelling the mechanism of Cardiotoxicity of Citalopram: Utilisation of mechanistic cardiac electrophysiology modelling with Simcyp Cardiac Safety Simulator to explore various hypotheses Poster Towards unravelling the mechanism of Cardiotoxicity of Citalopram: Utilisation of mechanistic cardiac electrophysiology modelling with Simcyp Cardiac Safety Simulator to explore various hypotheses Certara2019年8月28日
Mechanistic modelling of dermal drug absorption using the Simcyp Multi-phase Multi-layer MechDermA model: Case study of a transdermal patch formulation of weak base drug timolol Poster Mechanistic modelling of dermal drug absorption using the Simcyp Multi-phase Multi-layer MechDermA model: Case study of a transdermal patch formulation of weak base drug timolol Certara2019年8月28日
Toward Unravelling the Mechanism of Cardiotoxicity of Citalopram: Utilization of Mechanistic Cardiac Electrophysiology Modelling with Simcyp Cardiac Safety Simulator (CSS) to Explore Various Hypotheses Poster Toward Unravelling the Mechanism of Cardiotoxicity of Citalopram: Utilization of Mechanistic Cardiac Electrophysiology Modelling with Simcyp Cardiac Safety Simulator (CSS) to Explore Various Hypotheses Certara2019年8月28日
Application of a physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) model for prediction of drug-drug interactions (DDIs) involving the JAK1/2 inhibitor Ruxolitinib in Caucasians and Japanese Poster Application of a physiologically based pharmacokinetic/pharmacodynamic (PBPK/PD) model for prediction of drug-drug interactions (DDIs) involving the JAK1/2 inhibitor Ruxolitinib in Caucasians and Japanese Certara2019年8月28日
