Evaluating the efficiency of payload delivery by ADCs using a minimal PBPK model Poster Evaluating the efficiency of payload delivery by ADCs using a minimal PBPK model Certara2019年8月28日
APPLICATION OF A MULTI-COMPARTMENT PERMEABILITY-LIMITED LUNG MODEL TO PREDICT LUNG CONCENTRATIONS OF MOXIFLOXACIN IN VIRTUAL HUMAN SUBJECTS Poster APPLICATION OF A MULTI-COMPARTMENT PERMEABILITY-LIMITED LUNG MODEL TO PREDICT LUNG CONCENTRATIONS OF MOXIFLOXACIN IN VIRTUAL HUMAN SUBJECTS Certara2019年8月28日
Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis Poster Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis Certara2019年8月28日
Application of mechanistic PBPK modelling to evaluate the power of pharmacogenomics studies using OATP1B1 and rosuvastatin as an example Poster Application of mechanistic PBPK modelling to evaluate the power of pharmacogenomics studies using OATP1B1 and rosuvastatin as an example Certara2019年8月28日
APPLICATION OF PBPK AND BAYESIAN MODELLING FOR PREDICTION OF THE LIKELIHOOD OF INDIVIDUAL PATIENTS EXPERIENCING SERIOUS ADVERSE REACTIONS TO A STANDARD DOSE OF EFAVIRENZ Poster APPLICATION OF PBPK AND BAYESIAN MODELLING FOR PREDICTION OF THE LIKELIHOOD OF INDIVIDUAL PATIENTS EXPERIENCING SERIOUS ADVERSE REACTIONS TO A STANDARD DOSE OF EFAVIRENZ Certara2019年8月28日
DEVELOPMENT OF A PBPK MODEL FOR EFAVIRENZ THAT ACCOUNTS FOR AUTO-INDUCTION AND ITS EFFECT ON THE CYP2B6 SUBSTRATE BUPROPION Poster DEVELOPMENT OF A PBPK MODEL FOR EFAVIRENZ THAT ACCOUNTS FOR AUTO-INDUCTION AND ITS EFFECT ON THE CYP2B6 SUBSTRATE BUPROPION Certara2019年8月23日
Prediction of Midazolam Pharmacokinetics in Pregnant Women with Coeliac Disease using Simcyp Pregnancy PBPK Model Poster Prediction of Midazolam Pharmacokinetics in Pregnant Women with Coeliac Disease using Simcyp Pregnancy PBPK Model Certara2019年8月23日
Investigating Impacts of Model Parameters Correlations in Global Sensitivity Analysis: Determining the Most Influential Parameters of a Minimal PBPK Model of Midazolam Poster Investigating Impacts of Model Parameters Correlations in Global Sensitivity Analysis: Determining the Most Influential Parameters of a Minimal PBPK Model of Midazolam Certara2019年6月24日
PBPK’s Pivotal Role in Modern Drug Development: Busting Common Myths and Misconceptions White Paper PBPK’s Pivotal Role in Modern Drug Development: Busting Common Myths and Misconceptions This white paper addresses common PBPK myths and misconceptions and demonstrates how this approach is…Certara2019年2月4日
Using PBPK Models to Assess Fetal Drug Exposure Blog Using PBPK Models to Assess Fetal Drug Exposure The tragedy of thalidomide provides a cautionary tale about the potential for birth defects resulting…Certara2018年1月19日