Therapeutic Specialties Archives

Publication

Pharmacokinetics, Safety, and Tolerability of Teduglutide, a Glucagon-like Peptide-2 (GLP-2) Analog, Following Multiple Ascending Subcutaneous Administrations in Healthy Subjects

Teduglutide, a glucagon-like peptide-2 (GLP-2) analog, is currently being evaluated for the treatment of short-bowel…

Danielle Pillsbury2008年11月1日

Publication

Meta-analysis of the Diagnostic Accuracy of Transesophageal Echocardiography for Assessment of Atherosclerosis in the Ascending Aorta in Patients Undergoing Cardiac Surgery

Stroke after cardiac surgery may be caused by emboli emerging from an atherosclerotic ascending aorta…

Danielle Pillsbury2008年10月1日

Publication

Intestinal Metabolism and Transport of Drugs in Children: The Effects of Age and Disease

The presence of cytochrome P450 enzymes in the small bowel results in the reduced bioavailability…

Danielle Pillsbury2008年7月1日

Publication

Pain Relief Model for a COX-2 Inhibitor in Patients with Postoperative Dental Pain

The aim of this study was to develop a pain relief model for a cyclooxygenase…

Danielle Pillsbury2008年7月1日

Publication

Development of CYP2D6 and CYP3A4 in the First Year of Life

Recently, Blake et al . ‘‘Ontogeny of dextromethorphan O- and N-demethylation in the first year…

Danielle Pillsbury2008年5月1日

Publication

CYP2D6 is Primarily Responsible for the Metabolism of Clomiphene

Clomiphene is a first line treatment for anovulation, a common cause of infertility. Response to…

Danielle Pillsbury2008年4月30日

Publication

Inactivation of CYP2D6 by Methylenedioxymethamphetamine in Different Recombinant Expression Systems

Recombinantly expressed CYP450 systems (rCYPs) are often used to screen for irreversible/quasi-irreversible enzyme inhibitors during…

Danielle Pillsbury2007年9月1日

Publication

The Problems in Scaling Adult Drug Doses to Children

Many drugs are unlicensed in children and consequently their doses have been scaled down from…

Danielle Pillsbury2007年3月15日

Publication

Predictive Population Pharmacokinetic/Pharmacodynamic Model for a Novel COX-2 Inhibitor

The objectives of these analyses were to (1) develop a population pharmacokinetic/pharmacodynamic model for a…

Danielle Pillsbury2007年3月1日

Publication

Implications of Mechanism-based Inhibition of CYP2D6 for the Pharmacokinetics and Toxicity of MDMA

The aim of this study was to model the in vivo kinetic consequences of mechanism-based…

Danielle Pillsbury2006年11月1日

Powered by Translations.com GlobalLink Web Software

治療領域

Pharmacokinetics, Safety, and Tolerability of Teduglutide, a Glucagon-like Peptide-2 (GLP-2) Analog, Following Multiple Ascending Subcutaneous Administrations in Healthy Subjects

Meta-analysis of the Diagnostic Accuracy of Transesophageal Echocardiography for Assessment of Atherosclerosis in the Ascending Aorta in Patients Undergoing Cardiac Surgery

Intestinal Metabolism and Transport of Drugs in Children: The Effects of Age and Disease

Pain Relief Model for a COX-2 Inhibitor in Patients with Postoperative Dental Pain

Development of CYP2D6 and CYP3A4 in the First Year of Life

CYP2D6 is Primarily Responsible for the Metabolism of Clomiphene

Inactivation of CYP2D6 by Methylenedioxymethamphetamine in Different Recombinant Expression Systems

The Problems in Scaling Adult Drug Doses to Children

Predictive Population Pharmacokinetic/Pharmacodynamic Model for a Novel COX-2 Inhibitor

Implications of Mechanism-based Inhibition of CYP2D6 for the Pharmacokinetics and Toxicity of MDMA

メルマガ登録

クイックアクセス

ソリューション

お問合せ