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Metformin and Cimetidine: Physiologically-based Pharmacokinetic Modeling to Investigate Transporter Mediated Drug–drug Interactions

Author(s): Howard Burt, Sibylle Neuhoff, Lisa Almond, Gaohua Lu, Matthew Harwood, Masoud Jamei, Amin Rostami-Hodjegan, Geoffrey Tucker, Karen Rowland Yeo

Year: 2016年6月1日

Evolving Regulatory Landscape for Model Informed Drug Development (MIDD): Impact of the Draft ICH M15 Guidance

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Metformin and Cimetidine: Physiologically-based Pharmacokinetic Modeling to Investigate Transporter Mediated Drug–drug Interactions

Metformin and Cimetidine: Physiologically-based Pharmacokinetic Modeling to Investigate Transporter Mediated Drug–drug Interactions

Evolving Regulatory Landscape for Model Informed Drug Development (MIDD): Impact of the Draft ICH M15 Guidance

トランスレーショナル開発における中和ADA効果の薬物動態モデリング

CERTAINTY 2025: The power of Model-Informed Drug Development

Extrapolating AUC to Infinity

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