What is HPLC/UV?
In my series about bioanalysis for the pharmacokineticist, I thought I would start with the…
Nathan Teuscher2014年7月8日
What Can We Learn from Dose Normalization?
Dose normalization is a common calculation performed with pharmacokinetic parameters. The general process is to…
Certara2014年5月19日
Extrapolating AUC to Infinity
Area under the curve or AUC is a pharmacokinetic statistic used to describe the total…
Certara2014年2月24日
Simplifying Deconvolution
Deconvolution is used to evaluate the absorption kinetics of a drug. Unfortunately the term can…
Nathan Teuscher2014年1月13日
Cassette Dosing: Advantages and Challenges
Cassette dosing is a technique primarily used in drug discovery efforts in non-clinical studies to…
Nathan Teuscher2013年12月16日
What is GLP (Good Laboratory Practice)?
Good laboratory practice or GLP is a set of principles intended to assure the quality…
Certara2013年12月9日
Understanding Steady State Pharmacokinetics
“Steady state” is an important term in pharmacokinetics, but it can often seem a bit…
Certara2013年11月25日
What is Identifiability?
Developing models for pharmacokinetic or pharmacodynamic data requires creativity, patience, and hard work. Sometimes that…
Nathan Teuscher2013年11月18日
What is the -2LL or the Log-likelihood Ratio?
Understand the 2LL (Log-likelihood Ratio) and its role in statistical analysis. Explore how it aids…
Nathan Teuscher2013年10月28日
Using Sampling “Windows” for PK Blood Samples
One of the most common questions posed by clinical operations experts when including pharmacokinetic sampling…
Nathan Teuscher2013年10月15日
