Improved Translation of Clinical TCE Dosing with Mechanistic Modeling
要旨：Regulatory agencies recommend quantitative justifications for clinical dose selection. T-cell engagers (TCE) pose particular…
Certara2024年10月31日
Applications of a QSP Model of LNP mRNA Delivery for the Treatment of Crigler-Najjar Syndrome Type 1
Applications of a QSP Model of LNP mRNA Delivery for the Treatment of Crigler-Najjar Syndrome Type 1
要旨：Crigler-Najjar syndrome type 1 (CN1) is an autosomal recessive disease caused by a marked…
Certara2024年10月31日
Guiding Target and Lead Optimization for a Molecular Glue Degrader
Learn how to optimize drug properties for protein degrader therapeutics by exploring system characteristics.
Certara2024年10月31日
Capturing CAR T-cell Therapy Dynamics Through Mechanistic Modeling
要旨：Chimeric antigen receptor T (CAR T)-cell therapy has shown remarkable success in treating various…
Certara2024年10月31日
Physiologically Based Pharmacokinetic Modelling, an Integrative Approach to First in Human (FIH) Studies [APAC Webinar]
Physiologically Based Pharmacokinetic (PBPK) modelling is an integrative approach facilitating the optimal use of various…
Certara2024年10月31日
Early Feasibility Assessment: An Innovative Approach to Gain Confidence in Therapeutic Discovery
In this webinar Josh Apgar, PhD discusses Early Feasibility Assessment (EFA), a quantitative approach to early…
Certara2024年10月29日
Adapting Value Stories for Global Healthcare Markets
Explore how to tailor healthcare value stories to global market access strategies, addressing cultural nuances,…
Certara2024年10月28日
On-ramps to popPK: Building Better Models with GUI, Code, or Both
A critical component of popPK studies is popPK modeling, where mathematical models are developed to…
Certara2024年10月18日
RAPS Sponsored Webcast: Optimizing Pediatric Oncology Drug Development: A Comprehensive Overview
Developing safe and effective oncology medications for children presents unique challenges due to ethical considerations…
Certara2024年10月17日
