Best Practices for Annotated CRFs

The SDTM annotated CRF (aCRF) is a cumbersome submission document to create. It’s also highly important. It visually documents how data are mapped from the CRF to SDTM. Because this is mostly a manual task, it is key to know what makes a high-quality aCRF.

In this webinar, Amy Garrett reviews published guidance from regulatory agencies and provides best practices for CRF annotations. These practices ensure your aCRF meets current regulatory requirements and the needs of internal users.

We have received over 200 follow-up questions from you. That’s a lot of questions! So we decided to answer them in the below blog posts.

1. Annotation formatting
2. Document properties, bookmarking and table of contents
3. Multiple copies and/or multiple versions of forms
4. Not Submitted annotations and SDRG