Pharmacokinetic and Pharmacodynamic Modeling to Determine the Human Dose of ST-246(R) to Protect Against Smallpox
Although smallpox has been eradicated, the United States government considers it a "material threat" and…
webdev2013年3月1日
Pharmacokinetic and Pharmacodynamic Analysis of Efavirenz Dose Reduction Using an In Vitro-In Vivo Extrapolation Model
The pharmacokinetics (PK) of efavirenz (EFV) is characterized by marked inter-patient variability that correlates with…
webdev2012年10月1日
Pharmacokinetics and Pharmacodynamics of TBR-652, a Novel CCR5 Antagonist, in HIV-1-Infected, Antiretroviral Treatment-experienced and CCR5 Antagonist-naive Patients
TBR-652 is a novel CCR5 antagonist with potent in vitro anti-HIV activity. The objective of…
webdev2011年4月12日
Combining Drug-disease and Economic Modeling to Inform Drug Development Decisions
Drug-disease models and clinical trial simulations are increasingly being used to support trial design and…
webdev2001年11月1日
