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Publication

A Study to Examine the Relationship Between Metritis Severity and Depletion of Oxytetracycline in Plasma and Milk after Intrauterine Infusion

Metritis is a frequent problem in postpartum dairy cows. Intrauterine therapy with the antimicrobial oxytetracycline…

Certara2016年10月1日

Publication

Gulp1 is Associated with the Pharmacokinetics of PEGylated Liposomal Doxorubicin (PLD) in Inbred Mouse Strains

Certara2016年10月1日

Blog

Arming Adherence-based Drug Development with Pharmacometrics

The time is right to explore how sensor-enabled digital adherence monitoring systems can benefit patients,…

Certara2016年9月12日

Brochure

Phoenix NLME ― 現代のサイエンティストのための最新PK/PDモデリングソフトウェア

Phoenix NLMEは、使いやすく、習得しやすいPK/PDモデリングソフトウェアです。Built from the…

Certara2016年9月12日

Brochure

希少疾病と希少疾病用医薬品の開発

There are 7,000 rare diseases impacting 350 million patients worldwide, yet only 300 of these…

Certara2016年8月3日

Publication

Population Pharmacokinetics of Bevacizumab in Cancer Patients with External Validation

Certara2016年8月1日

Publication

Prediction of Altered Bile Acid Disposition Due to Inhibition of Multiple Transporters: An Integrated Approach Using Sandwich-cultured Hepatocytes, Mechanistic Modeling, and Simulation

Certara2016年8月1日

White Paper

モデルに基づくメタ解析（MBMA）：革新的な手法の誕生

MBMA integrates internal and external drug development data to inform proprietary commercial and R&D decisions.…

Certara2016年7月14日

Publication

Phase 1 Study Assessing the Pharmacokinetic Profile and Safety of Avibactam in Patients with Renal Impairment

Avibactam is a non-β-lactam β-lactamase inhibitor intended for use as a fixed-dose combination with ceftazidime…

Certara2016年7月12日

Publication

More Power to OATP1B1: An Evaluation of Sample Size in Pharmacogenetic Studies Using a Rosuvastatin PBPK Model for Intestinal, Hepatic, and Renal Transporter-mediated Clearances

Rosuvastatin is a substrate of choice in clinical studies of organic anion-transporting polypeptide (OATP)1B1- and…

Certara2016年7月1日

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