Predictive Performance of Caffeine Preterm PBPK Model and Effect of Time-Varying Physiology on Predictions Poster Predictive Performance of Caffeine Preterm PBPK Model and Effect of Time-Varying Physiology on Predictions Certara2019年10月17日
Prediction of Drug-Drug Interaction between Phenobarbital and Theophylline in Children using Physiologically-Based Pharmacokinetic Modelling Poster Prediction of Drug-Drug Interaction between Phenobarbital and Theophylline in Children using Physiologically-Based Pharmacokinetic Modelling Certara2019年10月17日
Development of a PBPK model for the prediction of Amiodarone pharmacokinetics in fed and fasted state using ADAM model Poster Development of a PBPK model for the prediction of Amiodarone pharmacokinetics in fed and fasted state using ADAM model Certara2019年10月17日
The Certara Quantitative Systems Toxicology & Safety (QSTS) Pharma Consortium: Overview and Invitation to Join Poster The Certara Quantitative Systems Toxicology & Safety (QSTS) Pharma Consortium: Overview and Invitation to Join Certara2019年10月17日
Quantitative Systems Toxicology Approach Integrates Simcyp PBPK and Core Hepatocyte Metabolism: a Case Study with Valproic Acid Poster Quantitative Systems Toxicology Approach Integrates Simcyp PBPK and Core Hepatocyte Metabolism: a Case Study with Valproic Acid Certara2019年10月16日
Prediction of mAb disposition in hepatic impairment – Evolocumab as a case study Poster Prediction of mAb disposition in hepatic impairment – Evolocumab as a case study Certara2019年10月15日
Use of a physiologically based pharmacokinetic – pharmacodynamic (PBPK-PD) model to guide dose adjustments to S-warfarin in different populations Poster Use of a physiologically based pharmacokinetic – pharmacodynamic (PBPK-PD) model to guide dose adjustments to S-warfarin in different populations Certara2019年10月15日
Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed PBPK Model of Ritonavir Norvir® Tablet Absorption in Humans Under Fasted and Fed State Conditions Poster Biopharmaceutic In Vitro In Vivo Extrapolation (IVIV_E) Informed PBPK Model of Ritonavir Norvir® Tablet Absorption in Humans Under Fasted and Fed State Conditions Certara2019年10月15日
Accounting for CYP2C19 mechanism based inhibition and CYP1A2 induction in a PBPK model for omeprazole Poster Accounting for CYP2C19 mechanism based inhibition and CYP1A2 induction in a PBPK model for omeprazole Certara2019年10月11日
Physiological verification of a geriatric population using the Simcyp R package Poster Physiological verification of a geriatric population using the Simcyp R package Certara2019年10月11日