Simcyp Archives

What’s New in the Simcyp Simulator v19?

2019年11月26日

This webinar explained how the latest updates in the Simcyp Simulator v19, Certara’s physiologically-based pharmacokinetic (PBPK) modeling and simulation platform, will support developing safer, more effective medications faster.

Predicting Human Oral Bioavailability: Comparison of In Vivo Animal (Rat- Dog- and Monkey) Studies versus Mechanistic In Vitro In Vivo Extrapolation (IVIVE) Based Predictions

2019年11月6日

By webdev

Fitting PBPK Model Parameters within Simcyp Engine Using Simcyp-R Package

2019年11月6日

By webdev

Development of a PBPK model for the prediction of Amiodarone pharmacokinetics in fed and fasted state using the Advanced Dissolution, Absorption and Metabolism (ADAM) model

2019年10月22日

By webdev

Development of a Permeability-Limited Cardiac Physiologically-Based Pharmacokinetic Model for Predicting Cardiac Exposure

2019年10月17日

By webdev

Dosing corrected for species differences in toxicokinetics using PBPK modelling predicts equivalent reactive metabolite burden following acetaminophen overdose

2019年10月17日

By webdev

Predicting Human Oral Bioavailability: Comparison of in vivo animal (rat, dog, and monkey) studies versus mechanistic in vitro in vivo extrapolation (IVIVE) based predictions

2019年10月17日

By webdev

Predictive Performance of Caffeine Preterm PBPK Model and Effect of Time-Varying Physiology on Predictions

2019年10月17日

By webdev

Prediction of Drug-Drug Interaction between Phenobarbital and Theophylline in Children using Physiologically-Based Pharmacokinetic Modelling

2019年10月17日

By webdev

Development of a PBPK model for the prediction of Amiodarone pharmacokinetics in fed and fasted state using ADAM model

2019年10月17日

By webdev

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Tag: Simcyp