Jaap MandemaChief Innovation Officer
Prior to joining Certara, Dr. Mandema founded Quantitative Solutions in 2005 after spending more than 18 years in clinical pharmacology research and consulting. In addition, he was Senior Vice President and Chief Scientific Officer at Pharsight from 1996 to 2004. Mandema joined Pharsight in its infancy and played a critical role in its growth into a public company whose modeling and simulation services are highly regarded across the industry. At Pharsight, he was responsible for the scientific leadership of the company, the development of novel methods and the implementation of these methods in new software products. He pioneered the building and modeling of clinical trial outcome databases in evaluating product profiles across competing drugs. Before Pharsight, Mandema was Director of New Products Discovery at ALZA Corporation, responsible for defining new product opportunities for ALZA’s delivery technologies.
Mandema’s research interests are applying modeling and simulation to optimize treatment strategies, trial designs, and drug development decision-making. He has published extensively and received several awards for his academic contributions, including the Tanabe Young Investigators Award from the American College of Clinical Pharmacology and the Leon Goldberg Young Investigator Award from the American Society for Clinical Pharmacology and Therapeutics. Mandema started his professional career as an assistant professor of pharmaceutical sciences at the department of anesthesia, Stanford University School of Medicine. He received his PhD (cum laude) from the division of pharmacology at the Center for Bio-pharmaceutical Sciences, University of Leiden and his MS (cum laude) from the School of Pharmacy, University of Utrecht, the Netherlands.