Pharmacokinetic Modeling of Neutralizing ADA Effects in Translational Development
Wednesday, June 18th - 11am ET
Danielle Pillsbury2025年5月21日
Extrapolating AUC to Infinity
AUC calculations are simple but nuanced. In this blog, we look at how to extrapolate…
Certara2025年5月15日
Calculating AUC (Linear and Log-linear)
AUC calculations are simple but nuanced. In this blog, we look at how to calculate…
Certara2025年4月2日
Accumulation: What It Means and How to Calculate It
2025年4月2日 In this blog, we look closely at drug accumulation ratio, to help…
Certara2025年4月2日
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Certara2025年3月24日
Safety of combined long-acting injectable cabotegravir and long-acting injectable rilpivirine in virologically suppressed adolescents with HIV (IMPAACT 2017/MOCHA): a phase 1/2, multicentre, open-label, non-comparative, dose-finding study
The IMPAACT 2017/MOCHA study, a phase 1/2 multicenter trial across five countries, assessed the safety,…
Danielle Pillsbury2025年3月20日
Postmarketing Assessment of Antibody–Drug Conjugates: Proof-of-Concept Using Model-Based Meta-Analysis and a Clinical Utility Index Approach
This study explores a model-based meta-analysis (MBMA) and a clinical utility index (CUI) approach to…
Danielle Pillsbury2025年3月4日
