Certara’s Vaccine Simulator is a cutting-edge tool that employs Quantitative Systems Pharmacology (QSP) modeling to determine optimal vaccine dosing strategies. By integrating data from extensive clinical studies, the Vaccine Simulator develops sophisticated models to answer critical “what-if” scenarios. Using 32 clinical datasets, 3 vaccines, 8 dosing regimens, and 10 biomarkers, a novel model was developed. This model is instrumental in identifying the best dosing strategies for various patient groups, including vulnerable populations like the elderly and children. Trusted by global pharmaceutical companies, the Vaccine Simulator has been presented to regulatory agencies, including the FDA, showcasing its reliability and impact.
Vaccine Simulator
Optimize vaccine strategies for better patient outcomes
Learn more about the Vaccine Simulator
QSP model to guide and inform vaccine dosing
Certara’s Vaccine Simulator is built on a robust foundation of QSP technology, calibrated with data from over 20 clinical cases. This innovative platform allows pharmaceutical companies to simulate trial outcomes, predict vaccine efficacy, and optimize dosing regimens.
Provides insights into patient-specific dosing strategies
Links biomarkers to clinical endpoints for comprehensive analysis
Validated through collaboration with seven major pharmaceutical companies
QSPの専門家紹介
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エキスパート
Rachel Rose
Sr Director, QSP
Rachel has 15 years’ experience in developing QSP and PBPK/PD models for a broad range of drug modalities from small molecules to biotherapeutics including therapeutic proteins, antibody drug conjugates, gene therapies and vaccines. Her current work is focused on developing mechanistic models to predict immunogenicity of biotherapeutics and vacc...
専門家に相談する関連情報
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サターラは、多様な治療領域に対応する定量的システム薬理学（QSP）プラットフォームモデルを提供しており、データ主導のインサイトにより医薬品開発の加速化を実現しています。当社のカスタマイズされたソリューションは、複雑な生物学的システムを統合し、研究および臨床現場における科学的な意思決定をサポートします。
Speak to a QSP expert
Learn about how Certara’s Vaccine Simulator can transform your vaccine development process.
Optimize vaccine dosing strategies with QSP
Simulate clinical outcomes for diverse patient populations
Trusted by leading pharmaceutical companies and regulatory agencies
