サターラの薬物相互作用コンサルティングサービスは、製薬研究者や薬事担当科学者が複雑な薬物相互作用を解読するのを支援します。By leveraging the scientist-curated DIDB and our team’s extensive expertise, we deliver actionable insights to improve clinical decision-making and ensure patient safety. Our services include literature and NDA reviews, mechanistic assessments, and evaluations of PK variability to guide study designs and optimize therapeutic outcomes.
薬物相互作用コンサルティングサービス
Get more value out of your Drug Interaction Database (DIDB) license
Learn more about drug interaction solutions consulting services
Draw on drug interaction expertise to improve clinical decision making
Shorter DIDB learning curve
Learn from the in-house team with expertise in drug metabolism, transport, pharmacokinetics, drug interactions and clinical pharmacology responsible for curating and maintaining DIDB
Decode drug interactions
Certara consultants are available to help pharmaceutical researchers and regulatory scientists meet their project goals, improve clinical decision making and ultimately, enhance patient safety.
More efficient problem solving
Intimate knowledge of the DIDB platform helps end users with highly specific and detailed database searches and outputs.
Examples of drug interaction solutions consulting services include, but are not limited to
Detailed mechanistic assessment of risk
Assess risk of drug-drug interactions between a drug candidate and known substrates and perpetrators or enzymes and transporters (including food and herbal products).
Review of literature and NDAs
Use this information to guide DDI study design, for example, in vitro evaluations, clinical studies and more.
Evaluation of PK variability
Evaluate PK variability of common drug substrates to guide calculation of the number of subjects.
Impact of hepatic and renal impairment
Optimize pricing and access strategies.
Impact of gene polymorphism of enzymes and transporters
Understand the impact of gene polymorphism of enzymes and transporters on drug exposure.
複雑な薬物間相互作用（DDI）メカニズムの洞察をご提供
Provide insight on complex mechanisms of DDIs based on most up-to-date scientific and mechanistic knowledge.
Meet our drug interactions consulting services leaders
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エキスパート
Isabelle Ragueneau-Majlessi, MD, MS
Distinguished Scientist, Drug Interaction Solutions
Dr. Ragueneau is a co-founder of the Drug Interaction Database (DIDB) and leads the Drug Interaction Solutions program.
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エキスパート
Jingjing Yu, MD, PhD
Director, Drug Interaction Solutions
Dr. Yu brings over 15 years of experience in drug metabolism and clinical pharmacology, and brings a unique expertise in the field of drug interactions gained through her work in both academia and industry.
専門家に相談する
関連情報
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Partner with Certara’s drug interaction experts to elevate your clinical decision-making processes. Our team is dedicated to providing innovative solutions and unparalleled support for your drug development needs.
Access in-depth literature and NDA reviews for regulatory submissions.
Leverage comprehensive mechanistic and PK variability evaluations.
Ensure patient safety with tailored insights into drug interactions.
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FAQs
What is the DIDB?
Certara’s Drug Interaction Database (DIDB) is the industry’s largest expertly curated database to assess drug interactions and safety.
How can Certara assist with NDA reviews?
Our consultants review NDAs to guide study designs and address regulatory requirements.
What services do you offer in drug interaction consulting?
We offer literature reviews, mechanistic risk assessments, and PK variability evaluations.
