We identify some innovative approaches to predicting overall patient benefit from investigational drugs to support development decisions. We then illustrate calculation of a probabilistic clinical utility index (CUI), an implementation of multiattribute utility that focuses on clinical attributes.
2009 年 07 月 1 日
Author(s): Bill Poland, Lee Hodge, Anis Khan, Robert Clemen, John Wagner, Kevin Dykstra, Rajesh Krishna
Year: 2009 年 07 月 1 日