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Tag: Model-Based Meta-Analysis (MBMA)

Quantify Chronic Lower Back Pain Clinical Outcomes Database

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The current version of the database includes clinical safety and efficacy information on treatment options currently approved or in development for chronic lower back pain. The current version of the database includes information on all systemic pharmacological interventions. This includes mono and combination therapy with NSAIDs, acetaminophen, opioids, COX-2 inhibitors, norepinephrine reuptake inhibitors, anti-NGF, anti-epileptic drugs (AEDs), antidepressants, and muscle relaxants.

Quantify Multiple Sclerosis Clinical Outcomes Database

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The current version of the database includes clinical safety and efficacy information on disease modifying therapies that are on the market or late stage clinical development for relapsing, remitting, and secondary progressive multiple sclerosis.

Quantify Neuropathic Pain Clinical Outcomes Database

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The current version of the database includes clinical safety and efficacy information on treatment options currently approved or in development for painful diabetic neuropathy (DPN), post herpetic neuralgia (PHN), or fibromyalgia. Information on older treatment options (such as tricyclic antidepressants) was included if they are used as active controls.

Quantify IPF Clinical Outcomes Database

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The Quantify IPF Clinical Outcomes Database contains data from randomized clinical trials assessing pharmacological interventions for treatment of idiopathic pulmonary fibrosis.

Quantify Glaucoma Clinical Outcomes Database

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The Quantify Glaucoma Clinical Outcomes Database is developed to document clinical safety and efficacy information from all randomized placebo and active controlled trials in patients with ocular hypertension or (open angle) glaucoma treated with latanoprost, bimatoprost, travoprost, tafluprost, dorzolamide, brinzolamide or timolol (timolol is included as control only). Trials in the database also include washout designs and add on designs.

CODEx Rheumatoid Arthritis Clinical Outcomes Database

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The current version of the database includes clinical safety and efficacy information on all biologics as well as newer synthetic DMARDs currently approved or in development for rheumatoid arthritis (RA). Information on older treatment options (MTX and other DMARDs) was included if they are used as active controls.

Quantify Chronic Kidney Disease Clinical Outcomes Database

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The current version of the database includes clinical safety and efficacy information on treatment options currently approved or in development for Chronic Kidney Disease (CKD) progression
in patients with Type 2 Diabetes Mellitus (T2DM) and overt albuminuria/proteinuria, as well as patients with IGA nephropathy.

Quantify CD Clinical Outcomes Database

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The current version of the database contains information from randomized controlled trails on all current biologic and small molecule drugs that are evaluated for moderate-to-severe Crohn’s disease in patients that failed conventional treatment.

Quantify AS Clinical Outcomes Database

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The Quantify AS Clinical Outcomes Database is developed to document clinical safety and efficacy information from randomized controlled trials investigating biologics currently approved or in development for ankylosing spondylitis (AS).

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