Leveraging Biosimulation to Inform Optimal Use of COVID-19 Vaccines

Being a team of results-oriented scientists working to address the medical challenges of an unprecedented pandemic has fueled Certara’s propensity for innovation. Since the early days of COVID-19, we have been working alongside pharmaceutical companies, global health foundations, academia, and regulators to advance therapies and vaccines. Key to our work has been building upon our … Continued

Virtual Patients Refine Search for Safe & Effective Immuno-oncology Combo Therapies

By Vijayalakshmi Chelliah, Georgia Lazarou, Piet van der Graaf and Andrzej Kierzek Immuno-oncology (IO) represents an elegant solution; it uses a patient’s own immune system to fight their cancer. Early IO research used monoclonal antibodies to induce an immune response from patients’ PD1/PD-L1 and CTLA4 receptors, which serve as immune system checkpoints, successfully achieving long-term … Continued

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