Tag: Simcyp
Former Director of Clinical Pharmacology at CDER Joins Certara’s Simcyp Scientific Advisory Board
Dr. Lawrence J. Lesko’s selection underscores biosimulation’s integral role in the drug development process PRINCETON, NJ – Aug. 20, 2015 – Certara®, the global biosimulation technology-enabled drug development company, today announced that Lawrence J. Lesko, PhD, has joined its Simcyp® Scientific Advisory Board (SAB). Dr. Lesko was Director of the Office of Clinical Pharmacology in … Continued
Mechanistic Modeling of Dermal Drug Absorption Using the Simcyp Multi-phase Multi-layer MechDermA Model: Case Study of a Transdermal Patch Formulation of Weak Base Drug Timolol
Certara Head of Simcyp Translational Science Appointed to Xenobiotica Editorial Board
PRINCETON, NJ – Aug. 10, 2015 – Certara®, the global biosimulation technology-enabled drug development company, today announced that Iain Gardner, Ph.D., its senior scientific advisor and head of Simcyp translational science, has been appointed to the Xenobiotica Editorial Board. Dr. Gardner will play an active role in the monthly journal’s peer-review process and help to … Continued
Certara Launches Its Simcyp In Vitro Analysis Toolkit to Improve Drug Discovery & Development
This new standalone solution is designed to meet the needs of early-stage drug discovery and development researchers. PRINCETON, NJ – 2015年7月29日 – Certara®, the global biosimulation technology-enabled drug development company, today announced the launch of its Simcyp In Vitro (Data) Analysis (SIVA) Toolkit, version 1.0. The SIVA Toolkit is designed to enable the … Continued
100 PBPK モデリングシミュレーションの理解に役立つ記事
As a company with a strong academic foundation, our scientists actively publish the results of their research in the form of conference abstracts and peer-reviewed papers. We’re proud to announce that our PBPK modeling and simulation group has hit a milestone of having published more than 100 papers since 2007. In this blog post, I’ll discuss … Continued
Establishment of Virtual Bioequivalence Using Population-based PBPK Modeling: Application to the Setting of Dissolution Limits
How to Revamp Your Approach to Conventional IVIVC Models
An IVIVC (in vitro-in vivo correlation) is a predictive mathematical model describing the relationship between the in vitro properties of a dosage form and the in vivo responses. Drug developers frequently find IVIVCs useful for a number of reasons: They can use dissolution tests as a surrogate for human bioequivalence (BE) studies. They can support … Continued
